crushing medication guidelines
Crushing the tablet destroyed the drugs sustained-release properties and led to rapid absorption of the entire 12-hour dose which resulted in sedation and respiratory depression. This may be to protect the stomach from the drug protect the drug from the stomach acid or to target the release of the drug past the stomach. Tablet Crushing Information For Patients B Tablet will disperse in greater than 2 minutes. . General advice Practical advice on dispersing tablets in water or crushing them is provided free on the NEWT website. Do not crush granules. Water may also be used. Slow-release capsules may be opened and granules dispersed in water. However tablet crushing may alter bioavailability of the active ingredients within the drug. Unlicensed and Licensed staff can crush medications. The new regulation states. The implications of crushing tablets and opening capsules and the formulations for which this is ...